|
Abstract
It was conducted a chamber analysis of scientific trends in solving the problems of
chlamydia in pigs and focusing on the most effective methods of the disease prevention
and the treatment of animals. It has been determined that chlamydia are positioned as
bacteria and viruses, and therefore are quite common among farm animals, and poultry:
about 90 million new cases of chlamydia disease in animals, in particular pigs, are
registered in the world. Some types of chlamydia threaten the health of people and
animals, reducing the productivity of the latter. Chlamydiae are Gram-negative, obligate
intracellular bacteria with a complex developmental cycle consisting of two stages, such
as the elementary body (infectious) and the reticulum body. This determines their latency
and resistance to antibiotics and other therapeutic drugs. It has been determined that
chlamydia are similar to viruses and have the ability to cause dangerous formations in
the body of animals. Chlamydial disease in pigs manifests as conjunctivitis, pneumonia,
and pseudomembranous or necrotizing enteritis, which is confirmed by the experimental
reproduction of the infection in gnotobiotic pigs using clinical isolates. In addition,
chlamydia is associated with pericarditis, polyarthritis and polyserositis in piglets and
numerous reproductive problems such as vaginal discharge from the sow, disruption of
the sexual cycle, abortions, mummification of fetuses, the birth of weak piglets, the
increased perinatal and neonatal mortality, as well as orchitis, epididymitis and urethritis
in boars. However, for most of these diseases, the ultimate role of chlamydia is not fully
defined.
Chlamydia is considered a pathogen in pigs, chlamydia tests are not performed in
most available veterinary diagnostic laboratories. Chlamydia often occurs together with
other pathogens, and this phenomenon complicates the recovery of pigs to a certain
extent. Infection of animals with chlamydia occurs as a result of direct contact of their
mucous membranes with the causative agent of the disease. The systematic control of the
presence of chlamydia in animals of the breeding herd will prevent a decrease in their
productivity, that is, the substantial economic losses. The study of chlamydia by the
molecular genetic method (PCR) will allow to identify sick animals and carry out their
illumination, which is the most promising and will ensure the detection of sick animals.
Key words: chlamydia, infection, bacteria, animal, pig, pathogenesis, symptoms,
diagnostic methods.
|
|
REFERENCES
- 1. Hammerschlag, M. R. (2002). The intracellular life of chlamydiae. Semin.
Pediatr Infect Dis., 13(4), 239–248. doi: 10.1053/spid.2002.127201
- 2. Willingan, D. A, & Beamer, P. D. (1955). Isolation of a transmissible
agent from pericarditis of swine. J. Am. Vet. Med. Assoc., 126, 118–122.
- 3. Guenov, I. (1961). Etudes sur la pericardite fibrineuse des porcelets due au
virus de l'ornithose. Bull. Off Int. Epizoot., 55, 1465–1473.
- 4. Borel, N., Polkinghorne, A., & Pospischil, A. (2018). A Review on
Chlamydial Diseases in Animals: Still a Challenge for Pathologists. Veterinary
Pathology, 55(3), 374–390. doi: 10.1177/0300985817751218.
- 5. Kölbl, O. (1969). Untersuchungen über das Vorkommen von
Miyagawanellen beim Schwein. Wiener Tierärztl Monatssch., 56, 355–361.
- 6. Kölbl, O. Burtscher, H, & Hebenstreit, J. (1970). Polyarthritis bei
Schlachtsweinen. Mikrobiologische, histologische und fleischhygienische
Untersuchungen und Aspekte. Wiener Tierärztl Monatssch, 57, 355–361.
- 7. Leonard, I., Wittenbrink, M. M., & Bisping, W. (1988). Nachweis von
Chlamydia psittaci im Kot von Schweinen. Berl Munch Tierärztl Wschr., 101, 124–128.
8. Plagemann, O. (1981). Chlamydien als Abortursache beim Schwein und
als Differentialdiagnose zum Smedi-Komplex. Tierärztl Umsch., 36, 842–846.
- 9. Rogers, D. G., Andersen, A. A, Hogg, A., Nielsen, D. L., & Huebert,
M. A. (1993). Conjunctivitis and Keratoconjunctivitis associated with Chlamydiae in
swine. J. Am. Vet. Med. Assoc., 203(9), 1321–1323.
- 10. Schiller, I, Koesters, R, Weilenmann, R, Thoma, R, Kaltenboeck, B, Heitz,
P, & Pospischil, A. (1997). Mixed infections with porcine Chlamydia
trachomatis/pecorum and infections with ruminant. Chlamydia psittaci serovar 1
associated with abortions in swine. Vet. Microbiol., 58(2–4), 251–260.
doi: 10.1016/S0378-1135(97)00154-5.
- 11. Szeredi, L, Schiller, I, Sydler, T, Guscetti, F., Heinen, E, Corboz, ... &
Pospischil, A. (1996). Intestinal Chlamydia in finishing pigs. Vet. Pathol., 33(4), 369–
374. doi: 10.1177/030098589603300401.
- 12. Unterweger, C, Inic-Kanada, A, Setudeh, S, Knecht, C, Duerlinger, S,
Stas, M., ... & Barisani-Asenbauer, T. (2021). Characteristics of Chlamydia suis Ocular
Infection in Pigs. Pathogens, 10, 1103. doi: 10.3390/pathogens10091103
- 13. Nie, L. B, Liang, Q. L, Zou, Y., Gao, Y. H., Zhao, Q., Hu, G. X., & Zhu,
X. Q. (2018). First Report of Chlamydia Seroprevalence in Farmed Wild Boars in China.
Vector-Borne Zoonotic Diseases, 18(9), 504–508. doi: 10.1089/vbz.2018.2272
- 14. Sheng, C. Y, Gong, Q. L., Ma, B. Y., Liu, Y., Ge, G. Y., Li, D. L., ... &
Du, R. (2021). Prevalence of Chlamydia in Pigs in China from 1985 to 2020: A
Systematic Review and Meta-Analysis. Vector-Borne Zoonotic Dis., 21(7), 517–533. doi:
10.1089/vbz.2020.2694.
- 15. Jelocnik, M., Taylor-Brown, A., O’Dea, С., Anstey, S., Bommana, S.,
Masters, N., ... & Polkinghorne, A. (2019). Detection of a range of genetically diverse
chlamydiae in Australian domesticated and wild ungulates. Transboundary and
Emerging Diseases, 66(3), 1132–1137. doi: 10.1111/tbed.13171
- 16. Wu-Wen, Sun, Nian-Zhang, Zhang, Yuan-Huan, Kang, Lei, Zhang &
Xiao-Feng, Shan (2020). First Report of Chlamydia Seroprevalence in Slaughter Pigs in
Shandong Province, Eastern China. Vector-Borne and Zoonotic Diseases, 20(1), 51–53.
doi: 10.1089/vbz.2019.2472.
- 17. Kieckens, E., Van den Broeck, L., Van Gils, M., Morré, S. & Vanrompay,
D. (2018). Co-Occurrence of Chlamydia suis DNA and Chlamydia suis-Specific
Antibodies in the Human Eye. Vector-Borne and Zoonotic Diseases, 18(12), 677–682.
doi: 10.1089/vbz.2017.2256.
- 18. Everett, K. D., Bush, R. M, & Andersen, A. A. (1999). Emended
description of the order Chlamydiales, proposal of Parachlamydiaceae fam. nov. and
Simkaniaceae fam. nov., each containing one monotypic genus, revised taxonomy of the
family Chlamydiaceae, including a new genus and five new species, and standards for
the identification of organisms. Int. J. Syst. Bacteriol., 49(2), 415–440. doi:
10.1099/00207713-49-2-415.
- 19. Kerr, K., Entrican, G., McKeever, D., & Longbottom, D. (2005).
Immunopathology of Chlamydophila abortus infection in sheep and mice. Res Vet Sci.,
78(1), 1–7. doi: 10.1016/j.rvsc.2004.08.004.
- 20. Everett, K. D. (2000). Chlamydia and Chlamydiales: more than meets the
eye. Vet. Microbiol. 75(2), 109–126. doi: 10.1016/S0378-1135(00)00213-3.
- 21. Van Gils, M., Aeby, S., Vanrompay, D., & Greub, G. (2015). Absence of
Chlamydia-like organisms in pigs. New Microbes and New Infections, 7, 31–32. doi:
10.1016/j.nmni.2015.04.007.
- 22. Ksonz, I. M. (2012). Khlamidiozy tvaryn [Chlamydia of animals]. Poltava
: Oriiana.
- 23. Taylor-Brown, A., & Polkinghorne, A. (2017). New and emerging
chlamydial infections of creatures great and small. New Microbes and New Infections,
18, 28–33. doi: 10.1016/j.nmni.2017.04.004.
- 24. Stephan, S., Guerra, D., Pospischil, A., Hilbe, M., Weissenböck, H.,
Novotný, L., & Borel. N. (2014). Chlamydiaceae and chlamydia-like organisms in free-
living small mammals in europe and afghanistan. Journal of Wildlife Diseases, 50(2),
195–204. doi: 10.7589/2013-08-194.
- 25. Ksonz, I. M., & Pochernyaev, K. F. (2010). The method of determining
the DNA of bacteria of the Chlamydiaceae family in the polymerase chain reaction by
amplifying a fragment of the gene of the main membrane protein (MOMP): pat. 51635
Ukraine: IPK A 61 K 39/118; statement 19.01.2010; published 26.07.2010, Bull. No. 14.
10. Kyiv : State Department of Intellectual Property
- 26. Ksonz, I. M., Pochernyaev, K. F., & Kurman A. F. (2006). The method of
determining DNA, causative agents of chlamydial infections in the multiplex polymerase
chain reaction: pat. 11834 Ukraine. Kyiv : State Department of Intellectual Property.
- 27. Ksonz, I. M., & Pochernyaev, K. F. (2008). The method of determining
the DNA of seven causative agents of chlamydial infections of mammals and birds in one
polymerase chain reaction: pat. 34868 Ukraine. Kyiv: State Department of Intellectual
Property.
|